Lesson Plan: B2.3.02

LESSON PLAN

Teacher	Subject	Period	Date	Year	Ability	LSA/Other Support
	Science

Context and Landmark Assessment	B2.3.02 Landmark Assessment: Progress Observation Opportunity

Remember to have high expectations

Lesson Title: Today we are learning about
What does the genetic code do?

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Focus on Knowledge, Skills and Understanding

Success Criteria:	You will show your learning by...
Students should be able to describe DNA as a polymer made from four different nucleotides. A sequence of three bases is the code for a particular amino acid. The order of bases controls the order in which amino acids are assembled to produce a particular protein. The long strands of DNA consist of alternating sugar and phosphate sections. Attached to each sugar is one of the four bases The DNA polymer is made up of repeating nucleotide units. Interpret a diagram of DNA structure but will not be required to reproduce it. (HT only) Students should be able to recall a simple description of protein synthesis explain simply how the structure of DNA affects the protein made describe how genetic variants may influence phenotype: a) in coding DNA by altering the activity of a protein: and b) in non-coding DNA by altering how genes are expressed (HT only) In the complementary strands a C is always linked to a G on the opposite strand and a T to an A. (HT only) Students are not expected to know or understand the structure of mRNA, tRNA, or the detailed structure of amino acids or proteins. (HT only) Students should be able to explain how a change in DNA structure may result in a change in the protein synthesised by a gene (HT only) Proteins are synthesised on ribosomes, according to a template. (HT only) Carrier molecules bring specific amino acids to add to the growing protein chain in the correct order (HT only) When the protein chain is complete it folds up to form a unique shape. This unique shape enables the proteins to do their job as enzymes, hormones or forming structures in the body such as collagen.

Success Criteria:

You will show your learning by...

Students should be able to describe DNA as a polymer made from four different nucleotides.
A sequence of three bases is the code for a particular amino acid.
The order of bases controls the order in which amino acids are assembled to produce a particular protein.
The long strands of DNA consist of alternating sugar and phosphate sections. Attached to each sugar is one of the four bases
The DNA polymer is made up of repeating nucleotide units. Interpret a diagram of DNA structure but will not be required to reproduce it.
(HT only) Students should be able to recall a simple description of protein synthesis
explain simply how the structure of DNA affects the protein made
describe how genetic variants may influence phenotype: a) in coding DNA by altering the activity of a protein: and b) in non-coding DNA by altering how genes are expressed
(HT only) In the complementary strands a C is always linked to a G on the opposite strand and a T to an A.
(HT only) Students are not expected to know or understand the structure of mRNA, tRNA, or the detailed structure of amino acids or proteins.
(HT only) Students should be able to explain how a change in DNA structure may result in a change in the protein synthesised by a gene
(HT only) Proteins are synthesised on ribosomes, according to a template.
(HT only) Carrier molecules bring specific amino acids to add to the growing protein chain in the correct order
(HT only) When the protein chain is complete it folds up to form a unique shape. This unique shape enables the proteins to do their job as enzymes, hormones or forming structures in the body such as collagen.

Think about how you can match the needs of ALL students

Keywords:

Ribosome: Organelle that carries out protein synthesis. (1)
Nucleotide: Subunit of DNA made of a sugar, phosphate group and one of 4 bases (A,T,C or G) (1)
Amino Acid: one of 24 different subunits joined to make a protein (1)
Polymer: A long molecule made of smaller repeating units joined (1)

Links: Literacy, Numeracy, SMSC, British values

Memory Anchor:

AFL/Key Questions:

What is DNA?
DNA is a polymer made of four different nucleotides.
What controls which amino acid is made during protien synthesis?
A sequence of three bases is the code for a particular amino acid.
What controls which protien is made during protien synthesis?
The order of bases controls the order in which amino acids are assembled to produce a particular protein.
What are the different parts of DNA strcuture?
The long strands of DNA consist of alternating sugar and phosphate sections. Attached to each sugar is one of the four bases
What is the structure of a DNA polymer?
The DNA polymer is made up of repeating nucleotide units.
What are the steps in protein synthesis? What happens in these steps?
The two steps in protein synthesis are transcription and translocation. During transcription an enzyme unwinds the DNA strands to make up two strands of RNA. Here complimentary bases match up with the RNA to form new strands. Then any sections of unused RNA are transcribed into proteins.
How does the structure of DNA affect the protien that is made during protien synthesis?
A set of three bases codes for a particular amino acid. The order of bases controls the order of animo acids, this controls what protien is made
How do genetic variants influence a persons phenotype through coding DNA and non coding DNA?
Coding DNA - by altering the activity of a protein Non-coding DNA - by altering how genes are expressed
What are the DNA base pairs?
In the complementary strands a C is always linked to a G on the opposite strand and a T to an A.
How can a change in DNA structure result in a change in the protein synthesised by a gene?
A differnet order of DNA base pairs will cause a different amino acid to be made, this in turn could produce a different protein
Where does protein synthesis take place in a cell?
Proteins are synthesised on ribosomes, according to a template.
What is the role of a carrier molecule in protein synthesis?
(HT only) Carrier molecules brings specific amino acids to add to the growing protein chain in the correct order
Why is a proteins unique shape important?
This unique shape enables the proteins to do their job as enzymes, hormones or forming structures in the body such as collagen.

Identify questions for high, middle, low and identify questioning techniques- Challenge questions

Learning Phases/Episodes

Think about how you can match the needs of ALL students
Differentiation: AGT, SEND, LLL, Disadvantaged
Remember to check for PROGRESS

Starter Activity	Differentiation and Challenge question/task
Students to copy and complete the keywords. Teacher reveals missing letters; Students correct mistakes; Discuss the scientific meanings of the words. Students to write down the definitions of the most important / new keywords. Discuss the 'Memory Anchor'. What does it show? How does it relate to the what we are learning about today (title)?

Think about PACE – Develop, consolidate and deepen knowledge, skills and understanding

Teacher or Student lead?	Differentiation and Challenge question/task

Progress Check	Extension

Remember to give time to apply knowledge, skills and understanding

Teacher or Student lead?	Differentiation and Challenge question/task

Progress Check	Extension

Teacher or Student lead?	Differentiation and Challenge question/task

Progress Check	Extension

Teacher or Student lead?	Differentiation and Challenge question/task

Progress Check	Extension

Plenary	Differentiation and Challenge question/task
Students to answer the 'Key Questions' with learning partners.
Progress Check Teacher to reveal and discuss the answers to the questions.	Extension What have learnt about the 'Big Ideas' today?

Homework	Differentiation and Challenge question/task